After going through a rough breakup, awkward and upbeat Jess (Zooey Deschanel) moves in with three single guys. Intelligent and witty Nick is an underachiever who took the bartender off ramp on his road to success. Schmidt obsesses over his social standing and looks at Jess as a personal project. Coach is a personal trainer who uses his athletic exterior to hide his shyness. Together with Jess's best friend Cece, they bond to form an unlikely, and dysfunctional, family.